• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: FOX{D1,D2}.p2

Z-value: 1.117

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Top targets:

Promoter	Score	Refseq	Gene	Description
chr8_-_87297283	11.624		Nfix	nuclear factor I/X
chr2_-_170232008	7.590		Bcas1	breast carcinoma amplified sequence 1
chr19_+_23215704	6.145	NM_010638	Klf9	Kruppel-like factor 9
chr13_-_94269673	6.096		Jmy	junction-mediating and regulatory protein
chr1_-_134603848	5.437	NM_001160318	Nfasc	neurofascin
chr10_-_8238569	5.097	NM_177387	Ust	uronyl-2-sulfotransferase
chr14_+_48740583	5.091		Peli2	pellino 2
chr15_+_3220994	5.072		Sepp1	selenoprotein P, plasma, 1
chr15_+_3220999	4.866		Sepp1	selenoprotein P, plasma, 1
chr9_+_45178267	4.750	NM_022004	Fxyd6	FXYD domain-containing ion transport regulator 6
chr8_+_24780132	4.387	NM_177086	Zmat4	zinc finger, matrin type 4
chr9_-_91255831	4.056		Zic1	zinc finger protein of the cerebellum 1
chr14_-_52533039	4.027		Ndrg2	N-myc downstream regulated gene 2
chr2_+_164311755	3.826	NM_026797	Dbndd2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_+_16951911	3.811	NM_029861	Cnrip1	cannabinoid receptor interacting protein 1
chrM_+_1550	3.741
chr10_+_59569052	3.613		Spock2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr14_+_48740495	3.583	NM_033602	Peli2	pellino 2
chr19_+_53403902	3.438	NM_010847	Mxi1	Max interacting protein 1
chr3_+_96361879	3.304	NM_001009935 NM_023719	Txnip	thioredoxin interacting protein
chr19_+_23215725	3.274		Klf9	Kruppel-like factor 9
chr7_+_120351012	3.257		Arntl	aryl hydrocarbon receptor nuclear translocator-like
chr18_+_69504145	3.088	NM_013685	Tcf4	transcription factor 4
chr9_+_45178521	3.083		Fxyd6	FXYD domain-containing ion transport regulator 6
chr1_-_182126032	3.013	NM_023341	Adck3	aarF domain containing kinase 3
chr11_-_107331865	2.988	NM_145823	Pitpnc1	phosphatidylinositol transfer protein, cytoplasmic 1
chr1_-_195068455	2.938	NM_001044751	Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1
chr9_+_96096690	2.873	NM_001184706 NM_001184708 NM_178667	Tfdp2	transcription factor Dp 2
chr10_+_59569206	2.852		Spock2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr14_-_19071459	2.828	NM_011584	Nr1d2	nuclear receptor subfamily 1, group D, member 2
chr2_+_164312087	2.769		Dbndd2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr7_-_52359079	2.704	NM_010189	Fcgrt	Fc receptor, IgG, alpha chain transporter
chr6_-_88791829	2.611		Abtb1	ankyrin repeat and BTB (POZ) domain containing 1
chr14_-_104215770	2.582		Ednrb	endothelin receptor type B
chr2_-_163470826	2.564		Serinc3	serine incorporator 3
chr15_+_99223622	2.542	NM_001171035	Tmbim6	transmembrane BAX inhibitor motif containing 6
chr2_-_163470787	2.499		Serinc3	serine incorporator 3
chr19_+_4855178	2.475		Ctsf	cathepsin F
chr10_-_76188683	2.385	NM_009933	Col6a1	collagen, type VI, alpha 1
chr7_-_87547589	2.317	NM_011046	Furin	furin (paired basic amino acid cleaving enzyme)
chr14_-_52532988	2.314		Ndrg2	N-myc downstream regulated gene 2
chr19_+_29999596	2.237	NM_133775	Il33	interleukin 33
chr1_+_155756310	2.204		Glul	glutamate-ammonia ligase (glutamine synthetase)
chr15_+_99223377	2.153	NM_001171034 NM_001171036 NM_026669	Tmbim6	transmembrane BAX inhibitor motif containing 6
chr12_-_85791897	2.151	NM_134042	Aldh6a1	aldehyde dehydrogenase family 6, subfamily A1
chr9_+_69137694	2.094		Rora	RAR-related orphan receptor alpha
chr12_-_101963277	2.091		Rps6ka5	ribosomal protein S6 kinase, polypeptide 5
chr19_+_7631935	2.070	NM_139269	Pla2g16	phospholipase A2, group XVI
chr6_-_87793459	2.060		Cnbp	cellular nucleic acid binding protein
chr1_+_179374783	2.048	NM_001012330	Zfp238	zinc finger protein 238
chr5_+_31350991	2.034	NM_027855	0610007C21Rik	RIKEN cDNA 0610007C21 gene
chr10_-_42722514	1.929		Sobp	sine oculis-binding protein homolog (Drosophila)
chr12_-_101963226	1.911	NM_153587	Rps6ka5	ribosomal protein S6 kinase, polypeptide 5
chr2_+_136539202	1.869		Snap25	synaptosomal-associated protein 25
chr12_-_11443284	1.866	NM_012038	Vsnl1	visinin-like 1
chr4_+_138012860	1.863		Camk2n1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chrM_+_409	1.852
chr18_+_9707574	1.794	NM_130449	Colec12	collectin sub-family member 12
chr14_+_54878898	1.789	NM_134076	Abhd4	abhydrolase domain containing 4
chr9_-_21822333	1.780		Elavl3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr6_-_124861656	1.715	NM_008479	Lag3	lymphocyte-activation gene 3
chr11_+_68908718	1.711		Per1	period homolog 1 (Drosophila)
chr3_-_27795287	1.686	NM_001164437	Tmem212	transmembrane protein 212
chr6_-_88791875	1.638		Abtb1	ankyrin repeat and BTB (POZ) domain containing 1
chr10_+_79578561	1.633		Stk11	serine/threonine kinase 11
chr11_+_3230733	1.623	NM_178149	Pik3ip1	phosphoinositide-3-kinase interacting protein 1
chr8_+_56122680	1.596		Gpm6a	glycoprotein m6a
chr15_-_66801198	1.557	NM_008681	Ndrg1	N-myc downstream regulated gene 1
chr6_-_71390481	1.557		Rmnd5a	required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr10_-_92773579	1.514		Elk3	ELK3, member of ETS oncogene family
chr9_+_70526702	1.512	NM_007399	Adam10	a disintegrin and metallopeptidase domain 10
chr11_-_54769546	1.504		Tnip1	TNFAIP3 interacting protein 1
chr17_+_43705388	1.493	NM_013737	Pla2g7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr17_+_25023618	1.485	NM_001163750 NM_001163751	Spsb3	splA/ryanodine receptor domain and SOCS box containing 3
chr9_-_83040061	1.485	NM_026122 NM_175074	Hmgn3	high mobility group nucleosomal binding domain 3
chr4_-_128483355	1.470	NM_001081098	Zfp362	zinc finger protein 362
chr4_+_94406190	1.460		Tek	endothelial-specific receptor tyrosine kinase
chr15_+_61817102	1.447		Myc	myelocytomatosis oncogene
chr9_-_30957394	1.425
chr15_-_96529121	1.418		Slc38a2	solute carrier family 38, member 2
chr4_+_97248556	1.395	NM_001122952	Nfia D130039L10Rik	nuclear factor I/A RIKEN cDNA D130039L10 gene
chr13_-_94269616	1.386	NM_021310	Jmy	junction-mediating and regulatory protein
chr2_+_164312023	1.372		Dbndd2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr16_-_22439642	1.352	NM_023794	Etv5	ets variant gene 5
chr2_+_136539143	1.333	NM_011428	Snap25	synaptosomal-associated protein 25
chr10_-_17954752	1.333	NM_144820	Ccdc28a	coiled-coil domain containing 28A
chr11_+_78137699	1.316	NM_009657	Aldoc	aldolase C, fructose-bisphosphate
chr9_-_45763300	1.314	NM_172257	Sidt2	SID1 transmembrane family, member 2
chr10_+_96079634	1.311	NM_007569	Btg1	B-cell translocation gene 1, anti-proliferative
chr3_+_52072302	1.305		Foxo1	forkhead box O1
chr2_+_127951773	1.277	NM_009754 NM_207680 NM_207681	Bcl2l11	BCL2-like 11 (apoptosis facilitator)
chr4_+_101180580	1.258	NM_001164584 NM_001164585	Dnajc6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr16_+_33829715	1.251	NM_001145884 NM_010580	Itgb5	integrin beta 5
chr4_+_101180625	1.231		Dnajc6	DnaJ (Hsp40) homolog, subfamily C, member 6
chr9_+_110235922	1.226		Scap	SREBF chaperone
chr1_+_51346108	1.224		Sdpr	serum deprivation response
chr10_+_115580947	1.217		Ptprr	protein tyrosine phosphatase, receptor type, R
chr14_+_56179818	1.215		Dcaf11	DDB1 and CUL4 associated factor 11
chr12_+_35731853	1.210	NM_001014973	Snx13	sorting nexin 13
chr14_-_30534966	1.203	NM_009785	Cacna2d3	calcium channel, voltage-dependent, alpha2/delta subunit 3
chr11_-_54769601	1.201		Tnip1	TNFAIP3 interacting protein 1
chr1_-_196957466	1.192		Cr1l	complement component (3b/4b) receptor 1-like
chr18_-_39649499	1.191		Nr3c1	nuclear receptor subfamily 3, group C, member 1
chr2_-_71205805	1.191		Slc25a12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr12_+_35731888	1.189		Snx13	sorting nexin 13
chr3_-_146433200	1.182	NM_001164198	Prkacb	protein kinase, cAMP dependent, catalytic, beta
chr5_-_123439064	1.180	NM_001003953	Kdm2b	lysine (K)-specific demethylase 2B
chr11_+_120094240	1.174	NM_198423	Bahcc1	BAH domain and coiled-coil containing 1
chr2_-_172765592	1.156	NM_007557	Bmp7	bone morphogenetic protein 7
chr1_-_172040852	1.152		Ddr2	discoidin domain receptor family, member 2
chr7_+_133920438	1.147	NM_025347 NM_026875	Ypel3	yippee-like 3 (Drosophila)
chr9_-_121404799	1.143	NM_031161	Cck	cholecystokinin
chr15_+_97614772	1.139	NM_026353	Slc48a1	solute carrier family 48 (heme transporter), member 1
chrM_+_6139	1.137
chr15_+_80541675	1.135	NM_144812	Tnrc6b	trinucleotide repeat containing 6b
chrX_+_133371611	1.135		Plp1	proteolipid protein (myelin) 1
chr2_+_181501718	1.115	NM_001171616 NM_008665	Myt1	myelin transcription factor 1
chrX_+_39502588	1.108	NM_001077712	Stag2	stromal antigen 2
chr11_-_118355393	1.105
chr18_-_60908267	1.103		Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr12_-_85791928	1.089		Aldh6a1	aldehyde dehydrogenase family 6, subfamily A1
chr17_+_70871444	1.085	NM_001128180	Dlgap1	discs, large (Drosophila) homolog-associated protein 1
chr6_-_5446277	1.077	NM_013743	Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4
chr19_+_23240506	1.072		Klf9	Kruppel-like factor 9
chr18_-_39078304	1.069	NM_010197	Fgf1	fibroblast growth factor 1
chr5_-_34530221	1.056		Mxd4	Max dimerization protein 4
chr1_+_59538966	1.055	NM_008057	Fzd7	frizzled homolog 7 (Drosophila)
chr11_-_86807216	1.055	NM_001005341	Ypel2	yippee-like 2 (Drosophila)
chr17_-_66234633	1.048		Ralbp1	ralA binding protein 1
chr16_-_85120798	1.044		App	amyloid beta (A4) precursor protein
chr3_+_90058166	1.037	NM_028881	Crtc2	CREB regulated transcription coactivator 2
chr2_+_67955769	1.033	NM_020283	B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr18_-_78320014	1.022		Slc14a1	solute carrier family 14 (urea transporter), member 1
chr2_-_51828440	1.017		Nmi	N-myc (and STAT) interactor
chr18_-_80904852	1.016	NM_001164111 NM_001164112 NM_016791	Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr2_+_91570249	1.015	NM_001080754 NM_172669	Ambra1	autophagy/beclin 1 regulator 1
chr9_-_45763233	1.009		Sidt2	SID1 transmembrane family, member 2
chr1_+_36568707	1.006	NM_001039551 NM_053186	Cnnm3	cyclin M3
chr11_+_43247209	1.002	NM_148673 NM_198936	Slu7	SLU7 splicing factor homolog (S. cerevisiae)
chr19_+_4855128	0.998	NM_019861	Ctsf	cathepsin F
chr3_-_51908927	0.997	NM_001004176	Maml3	mastermind like 3 (Drosophila)
chrM_+_11812	0.989
chr2_-_168427037	0.982	NM_001037178	Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr2_+_73150702	0.969	NM_029022	Scrn3	secernin 3
chr10_+_21602148	0.962		Sgk1	serum/glucocorticoid regulated kinase 1
chr5_+_148241736	0.961		Pan3	PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr3_+_34549057	0.953		Sox2	SRY-box containing gene 2
chrX_+_65931956	0.938		Fmr1	fragile X mental retardation syndrome 1 homolog
chr12_-_32635061	0.934		Hbp1	high mobility group box transcription factor 1
chr18_+_23468655	0.933		Dtna	dystrobrevin alpha
chr1_+_167693876	0.930	NM_011804	Creg1	cellular repressor of E1A-stimulated genes 1
chr13_-_53024983	0.927	NM_016709	Auh	AU RNA binding protein/enoyl-coenzyme A hydratase
chr6_+_53523365	0.923	NM_172728	Creb5	cAMP responsive element binding protein 5
chr2_-_71205587	0.916	NM_172436	Slc25a12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr11_-_86807135	0.915		Ypel2	yippee-like 2 (Drosophila)
chrX_+_65931715	0.912	NM_008031	Fmr1	fragile X mental retardation syndrome 1 homolog
chr18_+_69843730	0.909		Tcf4	transcription factor 4
chr17_+_75835208	0.908	NM_001166493	Rasgrp3	RAS, guanyl releasing protein 3
chr14_+_56179739	0.908	NM_001199009	Dcaf11	DDB1 and CUL4 associated factor 11
chr12_-_32184404	0.907	NM_134048	Cbll1	Casitas B-lineage lymphoma-like 1
chr6_+_88674398	0.902	NM_001166249 NM_011844	Mgll	monoglyceride lipase
chr11_+_98603186	0.901	NM_178060	Thra	thyroid hormone receptor alpha
chr2_-_84265422	0.894	NM_018782	Calcrl	calcitonin receptor-like
chr7_-_149558139	0.886	NM_177265	6330512M04Rik	RIKEN cDNA 6330512M04 gene
chr11_+_74433092	0.879	NM_001013784	E130309D14Rik	RIKEN cDNA E130309D14 gene
chr9_+_45178485	0.872		Fxyd6	FXYD domain-containing ion transport regulator 6
chr13_-_104710374	0.868	NM_001005868 NM_021563	Erbb2ip	Erbb2 interacting protein
chr15_-_58046428	0.865	NM_026346	Fbxo32	F-box protein 32
chr10_+_57514349	0.862	NM_020561	Smpdl3a	sphingomyelin phosphodiesterase, acid-like 3A
chr10_+_98486068	0.861		Atp2b1	ATPase, Ca++ transporting, plasma membrane 1
chr11_+_54251680	0.855	NM_173753	Fnip1	folliculin interacting protein 1
chr1_+_173053280	0.849		1700009P17Rik	RIKEN cDNA 1700009P17 gene
chr11_+_117623703	0.845		Tnrc6c	trinucleotide repeat containing 6C
chr15_-_88808967	0.844	NM_133241	Mlc1	megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
chr2_+_124436328	0.839		Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr2_-_163470841	0.835		Serinc3	serine incorporator 3
chr1_+_136312291	0.824		Adipor1	adiponectin receptor 1
chr11_-_106650166	0.819		Ddx5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr11_+_89892027	0.813		Tmem100	transmembrane protein 100
chr7_-_91838299	0.808		Zfand6	zinc finger, AN1-type domain 6
chr6_-_24477549	0.807		Ndufa5	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr11_-_101087738	0.804	NM_007970	Ezh1	enhancer of zeste homolog 1 (Drosophila)
chr1_+_145487825	0.790	NM_020025	B3galt2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr2_-_73150559	0.785	NM_025854	Cir1	corepressor interacting with RBPJ, 1
chr15_+_88890140	0.776	NM_001002005	Panx2	pannexin 2
chrX_+_7299332	0.765		Wdr45	WD repeat domain 45
chr8_+_68141935	0.764	NM_001166372	March1	membrane-associated ring finger (C3HC4) 1
chr5_-_149862867	0.764		Hmgb1	high mobility group box 1
chr13_-_61037894	0.763	NM_001145799	Ctla2a	cytotoxic T lymphocyte-associated protein 2 alpha
chr8_+_75095914	0.757	NM_144534	Nwd1 Tmem38a	NACHT and WD repeat domain containing 1 transmembrane protein 38A
chr10_+_79578529	0.748		Stk11	serine/threonine kinase 11
chr12_+_4133370	0.742	NM_001159536 NM_001159537	Adcy3	adenylate cyclase 3
chr18_+_61747381	0.730		Csnk1a1	casein kinase 1, alpha 1
chr17_+_35390491	0.728		Ddx39b	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr1_+_52176281	0.726	NM_009283	Stat1	signal transducer and activator of transcription 1
chr15_+_101974792	0.721		Igfbp6	insulin-like growth factor binding protein 6
chr5_+_143105467	0.712	NM_178398	Wipi2	WD repeat domain, phosphoinositide interacting 2
chr15_-_51823107	0.702		Rad21	RAD21 homolog (S. pombe)
chr4_+_132686434	0.697	NM_153423	Wasf2	WAS protein family, member 2
chrM_+_1091	0.693

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.56	3.79e-08	GO:0031323	regulation of cellular metabolic process
2.81	1.22e-07	GO:0048518	positive regulation of biological process
2.36	2.43e-07	GO:0019222	regulation of metabolic process
2.42	1.45e-06	GO:0080090	regulation of primary metabolic process
2.45	1.67e-06	GO:0060255	regulation of macromolecule metabolic process
4.29	3.90e-06	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.74	4.84e-06	GO:0048522	positive regulation of cellular process
2.57	1.55e-05	GO:0031326	regulation of cellular biosynthetic process
2.54	2.18e-05	GO:0009889	regulation of biosynthetic process
2.58	4.31e-05	GO:0010556	regulation of macromolecule biosynthetic process
2.52	4.47e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.67	5.26e-05	GO:0048519	negative regulation of biological process
2.50	5.84e-05	GO:0051171	regulation of nitrogen compound metabolic process
2.75	7.66e-05	GO:0048523	negative regulation of cellular process
2.57	7.91e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.50	9.52e-05	GO:0010468	regulation of gene expression
1.66	1.12e-04	GO:0050794	regulation of cellular process
2.63	1.21e-04	GO:0006355	regulation of transcription, DNA-dependent
3.25	1.43e-04	GO:0009893	positive regulation of metabolic process
3.95	1.77e-04	GO:0042127	regulation of cell proliferation
3.32	1.88e-04	GO:0031325	positive regulation of cellular metabolic process
2.58	1.91e-04	GO:0051252	regulation of RNA metabolic process
4.10	2.23e-04	GO:0010628	positive regulation of gene expression
4.92	2.48e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
4.22	3.29e-04	GO:0045893	positive regulation of transcription, DNA-dependent
4.16	4.06e-04	GO:0051254	positive regulation of RNA metabolic process
3.24	5.53e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.57	1.16e-03	GO:0050789	regulation of biological process
3.58	1.60e-03	GO:0031328	positive regulation of cellular biosynthetic process
3.51	2.11e-03	GO:0009891	positive regulation of biosynthetic process
3.68	2.13e-03	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.63	2.59e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
3.59	2.98e-03	GO:0051173	positive regulation of nitrogen compound metabolic process
1.52	3.10e-03	GO:0065007	biological regulation
5.03	8.06e-03	GO:0032583	regulation of gene-specific transcription
5.42	1.09e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
48.82	1.84e-02	GO:0006111	regulation of gluconeogenesis
2.01	2.01e-02	GO:0032502	developmental process
2.22	2.29e-02	GO:0048731	system development
2.06	2.35e-02	GO:0007275	multicellular organismal development
3.10	3.55e-02	GO:0042981	regulation of apoptosis
3.06	4.08e-02	GO:0043067	regulation of programmed cell death

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.75	2.84e-03	GO:0005634	nucleus
1.46	8.26e-03	GO:0043231	intracellular membrane-bounded organelle
1.46	8.86e-03	GO:0043227	membrane-bounded organelle
7.90	1.26e-02	GO:0019717	synaptosome
1.39	2.20e-02	GO:0043226	organelle
1.19	3.87e-02	GO:0005623	cell
1.19	3.87e-02	GO:0044464	cell part
1.38	4.03e-02	GO:0043229	intracellular organelle

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
2.54	1.96e-03	GO:0003677	DNA binding
1.36	7.01e-03	GO:0005488	binding
4.89	1.17e-02	GO:0016563	transcription activator activity
2.04	1.87e-02	GO:0003676	nucleic acid binding
3.19	2.62e-02	GO:0001071	nucleic acid binding transcription factor activity
3.19	2.62e-02	GO:0003700	sequence-specific DNA binding transcription factor activity
2.86	4.46e-02	GO:0030528	transcription regulator activity